About Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) is caused by a mutation in the survival motor neuron gene 1 (SMN1). In a healthy person, this gene produces a protein that is critical to the function of the nerves that control our muscles. Individuals with SMA don’t produce survival motor neuron (SMN) protein at high enough levels. Without this protein, those nerve cells cannot properly function and eventually die, leading to debilitating and sometimes fatal muscle weakness.
What Causes SMA?
SMA is caused by a mutation in the survival motor neuron gene 1 (SMN1) leading to debilitating muscle weakness. Individuals with SMA don't produce SMN protein at high enough levels.
Who Does SMA Affect?
Each year, thousands of infants in the U.S. and around the world are born with SMA. SMA also impacts children, teens, and adults from every background, race, and gender.
How Does SMA Affect Individuals?
Individuals with SMA have difficulty performing the basic functions of life, like breathing and swallowing. However, SMA does not affect a person’s ability to think, learn, and build relationships with others.
Every dollar raised with Cure SMA's events helps grow research, care, advocacy, and support programs that the SMA community depends on. We will ensure everyone with SMA –from infants to adults– have the chance to live a full and productive life.
Thousands of individuals with SMA and their families receive support and access Cure SMA resources each year. With the passionate support from people like you, we can meet the ever-changing needs of all people with SMA.
Empower the Community
Events across the country bring together people from coast-to-coast to raise awareness and build community. Whether you have a direct connection to SMA or not, everyone is invited to make a difference by fundraising for Cure SMA!